α-synuclein and cytosolic dopamine: stabilizing a bad situation
D Sulzer - Nature medicine, 2001 - nature.com
Nature medicine, 2001•nature.com
The intriguing finding that α-synuclein—a protein recently found to be mutated in some
familial cases of Parkinson disease—and cytosolic dopamine interact to form adducts that
stabilize a presumably toxic intermediate of fibril formation provides clues into the
mechanism of neurodegeneration.
familial cases of Parkinson disease—and cytosolic dopamine interact to form adducts that
stabilize a presumably toxic intermediate of fibril formation provides clues into the
mechanism of neurodegeneration.
The intriguing finding that α-synuclein—a protein recently found to be mutated in some familial cases of Parkinson disease—and cytosolic dopamine interact to form adducts that stabilize a presumably toxic intermediate of fibril formation provides clues into the mechanism of neurodegeneration.
nature.com