Regulation of mucin genes in chronic inflammatory airway diseases
JA Voynow, SJ Gendler, MC Rose - American journal of respiratory …, 2006 - atsjournals.org
JA Voynow, SJ Gendler, MC Rose
American journal of respiratory cell and molecular biology, 2006•atsjournals.orgIn this review, we summarize work over the past 15 years on mucin gene expression and
regulation in the lung, as well as how mucin gene expression is altered in chronic lung
diseases. This field owes a great debt to Carol Basbaum for her pioneering work in
dissecting signaling pathways regulating mucin gene expression and for her tremendous
energy in promoting the importance of understanding the basic pathogenic mechanisms that
drive mucus overproduction in cystic fibrosis, chronic obstructive pulmonary disease, and …
regulation in the lung, as well as how mucin gene expression is altered in chronic lung
diseases. This field owes a great debt to Carol Basbaum for her pioneering work in
dissecting signaling pathways regulating mucin gene expression and for her tremendous
energy in promoting the importance of understanding the basic pathogenic mechanisms that
drive mucus overproduction in cystic fibrosis, chronic obstructive pulmonary disease, and …
In this review, we summarize work over the past 15 years on mucin gene expression and regulation in the lung, as well as how mucin gene expression is altered in chronic lung diseases. This field owes a great debt to Carol Basbaum for her pioneering work in dissecting signaling pathways regulating mucin gene expression and for her tremendous energy in promoting the importance of understanding the basic pathogenic mechanisms that drive mucus overproduction in cystic fibrosis, chronic obstructive pulmonary disease, and asthma.
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