Although the fusion proteins EWS-ETS are uniquely associated with Ewing's sarcoma and
have been shown to have transformational properties, they are not the only determinants of
oncogenesis. Therefore, before molecular-based therapy can be initiated, a better
understanding of the molecular network specific to Ewing's sarcoma is mandatory.
Specimens from 31 patients with Ewing's sarcoma were analyzed immunhistochemically.
We found that human telomerase reverse transcriptase was expressed highly (78%) in …