Recent advances in our understanding of intercalated cells
SM Wall - Current opinion in nephrology and hypertension, 2005 - journals.lww.com
SM Wall
Current opinion in nephrology and hypertension, 2005•journals.lww.comThe molecular mechanisms of net H+/OH− secretion by intercalated cell subsets have been
largely defined over the past decade. Moreover, targeted genetic disruption of these
transporters has revealed novel roles, such as blood pressure regulation. Thus, some of
these transporters might be the target of future antihypertensive drugs.
largely defined over the past decade. Moreover, targeted genetic disruption of these
transporters has revealed novel roles, such as blood pressure regulation. Thus, some of
these transporters might be the target of future antihypertensive drugs.
Summary
The molecular mechanisms of net H+/OH− secretion by intercalated cell subsets have been largely defined over the past decade. Moreover, targeted genetic disruption of these transporters has revealed novel roles, such as blood pressure regulation. Thus, some of these transporters might be the target of future antihypertensive drugs.
Lippincott Williams & Wilkins