[HTML][HTML] Visual percepts evoked with an intracortical 96-channel microelectrode array inserted in human occipital cortex

E Fernández, A Alfaro, C Soto-Sánchez… - The Journal of …, 2021 - Am Soc Clin Investig
E Fernández, A Alfaro, C Soto-Sánchez, P Gonzalez-Lopez, AM Lozano, S Peña, MD Grima…
The Journal of clinical investigation, 2021Am Soc Clin Investig
In this issue of the JCI, the dream of restoring useful vision to blind individuals with
neurotechnology moves one step closer to realization. Fernández et al. implanted an
electrode array with 96 penetrating electrodes in the visual cortex of a blind patient who had
been without light perception for 16 years due to optic neuropathy. Remarkably, the patient
was able to perceive visual patterns created by passing current through array electrodes.
The use of a penetrating electrode array meant that action potentials from single neurons …
Abstract
In this issue of the JCI, the dream of restoring useful vision to blind individuals with neurotechnology moves one step closer to realization. Fernández et al. implanted an electrode array with 96 penetrating electrodes in the visual cortex of a blind patient who had been without light perception for 16 years due to optic neuropathy. Remarkably, the patient was able to perceive visual patterns created by passing current through array electrodes. The use of a penetrating electrode array meant that action potentials from single neurons could be recorded to study the neural response to stimulation. Compared with electrodes resting on the cortical surface, penetrating electrodes require one-tenth the current to create a visual percept. However, patterned electrical stimulation often fails to produce the expected percept for penetrating and surface electrode arrays, highlighting the need for further research to untangle the relationship between stimulus and perception.
The Journal of Clinical Investigation