Intact human immunodeficiency virus (HIV) reservoir estimated by the intact proviral DNA assay correlates with levels of total and integrated DNA in the blood during …
E Papasavvas, L Azzoni, BN Ross… - Clinical Infectious …, 2021 - academic.oup.com
E Papasavvas, L Azzoni, BN Ross, M Fair, Z Yuan, K Gyampoh, A Mackiewicz, AC Sciorillo…
Clinical Infectious Diseases, 2021•academic.oup.comAccurate characterization of the human immunodeficiency virus (HIV) reservoir is imperative
to develop an effective cure. HIV was measured in antiretroviral therapy-suppressed
individuals using the intact proviral DNA assay (IPDA), along with assays for total or
integrated HIV DNA, and inducible HIV RNA or p24. Intact provirus correlated with total and
integrated HIV.
to develop an effective cure. HIV was measured in antiretroviral therapy-suppressed
individuals using the intact proviral DNA assay (IPDA), along with assays for total or
integrated HIV DNA, and inducible HIV RNA or p24. Intact provirus correlated with total and
integrated HIV.
Abstract
Accurate characterization of the human immunodeficiency virus (HIV) reservoir is imperative to develop an effective cure. HIV was measured in antiretroviral therapy-suppressed individuals using the intact proviral DNA assay (IPDA), along with assays for total or integrated HIV DNA, and inducible HIV RNA or p24. Intact provirus correlated with total and integrated HIV.
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