Fecal microbial transplantation for diseases beyond recurrent clostridium difficile infection
GR D'Haens, C Jobin - Gastroenterology, 2019 - Elsevier
GR D'Haens, C Jobin
Gastroenterology, 2019•ElsevierAs microbiome research has moved from associative to mechanistic studies, the activities of
specific microbes and their products have been investigated in the development of
inflammatory bowel diseases, cancer, metabolic syndrome, and neuropsychiatric disorders.
Findings from microbiome research have already been applied to the clinic, such as in fecal
microbiota transplantation for treatment of recurrent Clostridium difficile infection. We review
the evidence for associations between alterations in the intestinal microbiome and …
specific microbes and their products have been investigated in the development of
inflammatory bowel diseases, cancer, metabolic syndrome, and neuropsychiatric disorders.
Findings from microbiome research have already been applied to the clinic, such as in fecal
microbiota transplantation for treatment of recurrent Clostridium difficile infection. We review
the evidence for associations between alterations in the intestinal microbiome and …
As microbiome research has moved from associative to mechanistic studies, the activities of specific microbes and their products have been investigated in the development of inflammatory bowel diseases, cancer, metabolic syndrome, and neuropsychiatric disorders. Findings from microbiome research have already been applied to the clinic, such as in fecal microbiota transplantation for treatment of recurrent Clostridium difficile infection. We review the evidence for associations between alterations in the intestinal microbiome and gastrointestinal diseases and findings from clinical trials of fecal microbiota transplantation. We discuss opportunities for treatment of other diseases with fecal microbiota transplantation, based on findings from small clinical and preclinical studies.
Elsevier
