Preeclampsia: pathogenesis, prevention, and long-term complications
B Jim, SA Karumanchi - Seminars in nephrology, 2017 - Elsevier
Preeclampsia continues to afflict 5% to 8% of all pregnancies throughout the world and is
associated with significant morbidity and mortality to the mother and the fetus. Although the
pathogenesis of the disorder has not yet been fully elucidated, current evidence suggests
that imbalance in angiogenic factors is responsible for the clinical manifestations of the
disorder, and may explain why certain populations are risk. In this review, we begin by
demonstrating the roles that angiogenic factors play in pathogenesis of preeclampsia and its …
associated with significant morbidity and mortality to the mother and the fetus. Although the
pathogenesis of the disorder has not yet been fully elucidated, current evidence suggests
that imbalance in angiogenic factors is responsible for the clinical manifestations of the
disorder, and may explain why certain populations are risk. In this review, we begin by
demonstrating the roles that angiogenic factors play in pathogenesis of preeclampsia and its …
