[HTML][HTML] Interaction of arrestins with intracellular domains of muscarinic and α2-adrenergic receptors
G Wu, JG Krupnick, JL Benovic, SM Lanier - Journal of Biological Chemistry, 1997 - ASBMB
The intracellular domains of G-protein-coupled receptors provide sites for interaction with
key proteins involved in signal initiation and termination. As an initial approach to identify
proteins interacting with these receptors and the receptor motifs required for such
interactions, we used intracellular subdomains of G-protein-coupled receptors as probes to
screen brain cytosol proteins. Peptides from the third intracellular loop (i3) of the M 2-
muscarinic receptor (MR)(His 208–Arg 387), M 3-MR (Gly 308–Leu 497), or α 2A/D …
key proteins involved in signal initiation and termination. As an initial approach to identify
proteins interacting with these receptors and the receptor motifs required for such
interactions, we used intracellular subdomains of G-protein-coupled receptors as probes to
screen brain cytosol proteins. Peptides from the third intracellular loop (i3) of the M 2-
muscarinic receptor (MR)(His 208–Arg 387), M 3-MR (Gly 308–Leu 497), or α 2A/D …
