[HTML][HTML] The N-terminal domain of the R28 protein promotes emm28 group A Streptococcus adhesion to host cells via direct binding to three integrins
A Weckel, D Ahamada, S Bellais, C Méhats… - Journal of Biological …, 2018 - ASBMB
Group A Streptococcus (GAS) is a human-specific pathogen responsible for a wide range of
diseases, ranging from superficial to life-threatening invasive infections, including
endometritis, and autoimmune sequelae. GAS strains express a vast repertoire of virulence
factors that varies depending on the strain genotype, and many adhesin proteins that enable
GAS to adhere to host cells are restricted to some genotypes. GAS emm28 is the third most
prevalent genotype in invasive infections in France and is associated with gyneco …
diseases, ranging from superficial to life-threatening invasive infections, including
endometritis, and autoimmune sequelae. GAS strains express a vast repertoire of virulence
factors that varies depending on the strain genotype, and many adhesin proteins that enable
GAS to adhere to host cells are restricted to some genotypes. GAS emm28 is the third most
prevalent genotype in invasive infections in France and is associated with gyneco …
